E38N interferon gamma polypeptide variants

Drug – bio-affecting and body treating compositions – Lymphokine – Interferon

Reexamination Certificate

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C424S085400, C424S185100, C530S351000, C435S069510

Reexamination Certificate

active

10369495

ABSTRACT:
A conjugate exhibiting interferon gamma activity and comprising at least one first non-polypeptide moiety covalently linked to an IFG polypeptide, the polypeptide comprising an amino acid sequence that differs from that of a parent IFNG polypeptide in at least one introduced and/or at least one removed amino acid residue comprising an attachment group for the non-polypeptide moiety. The conjugate may be used for treatment of various diseases.

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