Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-05-11
1996-11-26
Ulm, John
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4351723, 43525233, 4353201, C12N 121, C12N 1572
Patent
active
055784640
ABSTRACT:
Strains of E. coli are provided which are capable of secreting heterologous recombinant proteins through the outer cell wall and directly into the culture medium. Methods are also provided for making and identifying such strains, and for using them to make heterologous proteins that have high biological activity, without the need for cell disruption.
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Lunn Charles A.
Narula Satwant K.
Reim Richard L.
Dulak Norman C.
Gould James M.
Schering Corporation
Ulm John
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