Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 11 to 14 amino acid residues in defined sequence
Patent
1989-07-06
1991-05-21
Lee, Lester L.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
11 to 14 amino acid residues in defined sequence
530302, 530317, 514809, C07K 712, C07K 706
Patent
active
050176897
ABSTRACT:
Cyclic disulfide and linear dynorphin Dyn A.sub.1-11 and dynorphin Dyn A.sub.1-13 analogs which are highly specific for .kappa. opioid receptors. These analogs are useful in pharmaceutical compositions and for the analysis of opioid receptor/ligand interactions.
REFERENCES:
patent: 4148786 (1979-04-01), Sarantakis
patent: 4518711 (1985-05-01), Hruby et al.
patent: 4684620 (1987-08-01), Hruby et al.
Civelli et al., Proc. Natl. Acad. Sci., U.S.A., vol. 82, 1985, pp. 4291-4295.
Hruby Victor
Kawasaki Andrew
Arizona Technology Development Corporation
Davenport Avis M.
Lee Lester L.
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