Dynamic monitoring of cell adhesion and spreading using the...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...

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C435S402000

Reexamination Certificate

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07732127

ABSTRACT:
The present invention includes devices and methods for dynamically monitoring cell adhesion and cell spreading. Cells are added to a microelectronic cell sensor array operably connected to an impedance analyzer. The device also includes a coating including biological molecule or organic compound capable of interacting with the cell. Cell adhesion and cell mobility is determined by detecting changes in impedance and comparing impedance or cell index values between samples.

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