Chemistry: analytical and immunological testing – Automated chemical analysis – Utilizing a centrifuge or compartmented rotor
Patent
1987-12-28
1991-03-12
Wax, Robert A.
Chemistry: analytical and immunological testing
Automated chemical analysis
Utilizing a centrifuge or compartmented rotor
422 72, 422237, 435 2, 436177, 436179, G01N 110, G01N 930
Patent
active
049993046
ABSTRACT:
A centrifuge for separating constituents of fluids, diluting the constituents and inoculating a reagent includes a spinning assembly for spinning a processor member. The processor member includes fluid and diluent compartments, separation chambers for a fluid and for a diluent, a mixing chamber, and a reagent chamber. The fluid compartment is in communication with the fluid separation chamber by a first passage. The diluent compartment and diluent separation chamber are communicated by a second passage. The first and second passages are oriented such that centrifugal force moves the fluid and diluent through the first and second passages into the respective chambers. The chambers are aligned to prevent outflow under the influence of centrifugal force but to allow outflow into measuring passages upon braking the spinning of the processor member. Spinning the processor member after braking generates a centrifugal force moving the fluid and diluent through the measuring passages into a mixing chamber. Braking the spinning of the processor member again applies a braking force on the mixed fluid and diluent moving this mixture into the reagent chamber.
REFERENCES:
patent: 3151073 (1960-10-01), Anthon
patent: 3795451 (1974-03-01), Mailen
patent: 3829223 (1974-08-01), Hamel
patent: 3899296 (1975-08-01), Mailen et al.
patent: 4284602 (1981-08-01), Kelton et al.
patent: 4740472 (1988-04-01), Burtis et al.
patent: 4814282 (1989-03-01), Holen et al.
Coe Roger N.
Miles Inc.
Waack Janelle D.
Wax Robert A.
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