Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Diagnostic or test agent produces in vivo fluorescence
Reexamination Certificate
2003-10-07
2008-10-21
Jones, D. L (Department: 1618)
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Diagnostic or test agent produces in vivo fluorescence
C424S001110, C424S001650, C424S009100, C424S009300, C424S009400, C424S009500, C548S146000
Reexamination Certificate
active
07438894
ABSTRACT:
Highly hydrophilic indole and benzoindole derivatives that absorb and fluoresce in the visible region of light are disclosed. These compounds are useful for physiological and organ function monitoring. Particularly, the molecules of the invention are useful for optical diagnosis of renal and cardiac diseases and for estimation of blood volume in vivo.
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Achilefu Samuel
Bugaj Joseph E.
Dorshow Richard B.
Periasamy Muthunadar P.
Rajagopalan Raghavan
Jones D. L
Mallinckrodt Inc.
Thompson Hine LLP
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