Dyes for organ function monitoring

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Diagnostic or test agent produces in vivo fluorescence

Reexamination Certificate

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C424S001110, C424S001650, C424S009100, C424S009300, C424S009400, C424S009500, C548S146000

Reexamination Certificate

active

07438894

ABSTRACT:
Highly hydrophilic indole and benzoindole derivatives that absorb and fluoresce in the visible region of light are disclosed. These compounds are useful for physiological and organ function monitoring. Particularly, the molecules of the invention are useful for optical diagnosis of renal and cardiac diseases and for estimation of blood volume in vivo.

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