Dye conjugates of nucleotides and other biological substances

Details Dye conjugates of nucleotides and other biological substances Dye conjugates of nucleotides and other biological substances

2011-07-26

2011-07-26

Riley, Jezia (Department: 1637)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S005000, C435S007100, C435S007200, C540S465000, C540S472000, C548S427000, C548S455000, C548S469000

Reexamination Certificate

active

07985552

ABSTRACT:
Chemically reactive carbocyanine dyes that are intramolecularly crosslinked between the 1-position and 3′-position, their bioconjugates and their uses are described. 1,3′-crosslinked carbocyanines are superior to those of conjugates of spectrally similar 1,1′-crosslinked or non-crosslinked dyes. The invention includes derivative compounds having one or more benzo nitrogens.

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Chen, Ping, et al., “Structure and solvent effective on the photostability of indolenine cyanine dyes,” Elsevier Science Ltd., Dyes and Pigments (1999) vol. 41, pp. 227-331.

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