Dye compounds

Details Dye compounds Dye compounds

2011-07-05

2011-07-05

Riley, Jezia (Department: 1637)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C422S067000, C536S024300, C536S026600, C546S026000

Reexamination Certificate

active

07972789

ABSTRACT:
The present disclosure provides compounds that may be used as chromogens, fluorochromes, or as both. Said compounds may further be used as substrate for at least one enzyme, wherein said enzyme is capable of processing an aromatic amine group (—NH2), an aromatic hydroxyl group (—OH), or an aromatic phosphate group (—PO4). Furthermore, the present disclosure also provides methods for precipitating said compounds as well as methods for detecting a target using said compounds. Even further, kits comprising said compounds are disclosed. Said compounds may be used in any method utilizing a fluorochrome, a chromogen, or both.

REFERENCES:
patent: 5268486 (1993-12-01), Waggoner et al.
patent: 5486616 (1996-01-01), Waggoner et al.
patent: 5569587 (1996-10-01), Waggoner
patent: 5839091 (1998-11-01), Rhett et al.
patent: 5948359 (1999-09-01), Kalra et al.
patent: 6183693 (2001-02-01), Bogen et al.
patent: 6352861 (2002-03-01), Copeland et al.
patent: 6686145 (2004-02-01), Waggoner et al.
patent: 0 747 700 (1996-12-01), None
patent: 0 747 700 (1996-12-01), None
patent: 0 747 448 (2002-11-01), None
patent: 2 089 055 (1982-06-01), None
patent: WO 00/75237 (2000-12-01), None
patent: WO 2004/057307 (2004-07-01), None
patent: WO 2004/057308 (2004-07-01), None
patent: WO 2004/058404 (2004-07-01), None
patent: WO 2004/058404 (2004-07-01), None
patent: WO 2004/058950 (2004-07-01), None
patent: WO 2004/059284 (2004-07-01), None
patent: WO 2004/059284 (2004-07-01), None
patent: WO 2004/059287 (2004-07-01), None
patent: WO 2004/059287 (2004-07-01), None
patent: WO 2004/059288 (2004-07-01), None
patent: WO 2004/059288 (2004-07-01), None
patent: WO 2004/059297 (2004-07-01), None
patent: WO 2004/059441 (2004-07-01), None
patent: WO 2004/059441 (2004-07-01), None
patent: WO 2004/065491 (2004-08-01), None
patent: WO 2007/059779 (2007-05-01), None
Stratagene (Catalog 1988, p. 39).
Ushomirskii et al. (Zhurnal Prikladnoi Spektroskopii (1984), 40(4),593-9). Abstract only.
Beilstein Database Accession No. 3894857, XP-002403557, Al'perowitsch et al.,Zh. Obshch. Khim., 1959, vol. 29, pp. 989-994.
Beilstein Database Accession No. 3895448, XP-002403558, Al'perowitsch et al.,Zh. Obshch. Khim., 1959, vol. 29, pp. 989-994.
Beilstein Database Accession No. 3895599, XP-002403566, Al'perowitsch et al.,Zh. Obshch. Khim., 1959, vol. 29, pp. 989-994.
Beilstein Database Accession No. 4027742, XP-002403555, Lifshitz et al.,J. Gen. Chem. USSR(Eng. Trans,), 1968, vol. 38, pp. 1965-1969.
Beilstein Database Accession No. 9087488, XP-002403569, Kabatc et al.,J. Chem. Soc. Perkin Trans. 2, 2002, vol. 2, pp. 287-295.
Beilstein Database Accession No. 9091355, XP-002403571, Kabatc et al.,J. Chem. Soc. Perkin Trans. 2, 2002, vol. 2, pp. 287-295.
Beilstein Database Accession No. 9092060, XP-002403572, Kabatc et al.,J. Chem. Soc. Perkin Trans. 2, 2002, vol. 2, pp. 287-295.
Bystryak, S.M. et al., “Photochemical amplification for horseradish peroxidase-mediated immunosorbent assay,”Anal. Biochem., 1992, vol. 202, pp. 390-393.
Chao, J. et al., “Immunofluorescence signal amplification by the enzyme-catalyzed deposition of a fluorescent reporter substrate (CARD),”Cytometry, 1996, vol. 23, pp. 48-53.
Johnstone, A.P. and Turner, M.W., eds.,Immunochemistry 2-A Practical Approach, Oxford University Press, 1997, pp. 71-130.
Kemeny, D.M., “Enzyme-linked immunoassays,” pp. 147-175 inImmunochemistry 1—A Practical Approach, Johnstone, A.P. et al., IRL Press, 1997.
Moreau, M. et al., “Synthèse d'indomonocarbocyanines à elimination biliaire sélective: Étude expérimentale chez l'animal,”Eur. J. Med. Chem., Chimica Therapeutica, 1974, vol. 9, No. 3, pp. 274-280.
Mujumdar, R.B. et al., “Cyanine dye labeling reagents containing isothiocyanate groups,”Cytometry, 1989, vol. 10, pp. 11-19.
Noland, W.E. et al., “Nitration of indoles. III. Polynitration of 2-alkylindoles,”J. Am. Chem. Soc., 1990, vol. 30, pp. 3457-3469.
Pham, W. et al., “Synthesis and application of a water-soluble near-infrared dye for cancer detection using optical imaging,”Bioconjugate Chem., 2005, vol. 16, pp. 735-740.
Self, C.H., “Enzyme amplification—a general method applied to provide an immunoassisted assay for placental alkaline phosphatase,”J. Immunol. Methods, 1985, vol. 76, pp. 389-393.
Shragina, L. et al., “Searching for photochromic liquid crystals: Spironaphthoxazine substituted with a mesogenic group,”Liquid Crystals, 1990, vol. 7, pp. 643-655.

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