Dye compositions and methods for film coating tablets and the li

Details Dye compositions and methods for film coating tablets and the li Dye compositions and methods for film coating tablets and the li

1993-02-24

1995-05-02

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424474, 424480, 424481, 424482, 427 214, 106402, A61K 936

Patent

active

054117461

ABSTRACT:
An improved dye composition for use in coating tablets and the like is constituted by a stable, aqueous suspension containing a water-soluble, nontoxic dye, an opacifying agent which may be titanium dioxide or iron oxide an immobilizing agent for immobilizing the dye and preventing it from migrating when applied to a tablet or the like, the immobilizing agent being constituted by a nontoxic metal salt present in an amount of from approximately 0.1 to 10 equivalents of metal per mole of dye, and water. The suspension may also contain a film-forming, water-soluble or water-dispersible edible polymer and a plasticizer. These compositions are used in lieu of lake compositions to produce tablets and the like with uniform, non-mottled coatings.

REFERENCES:
patent: 4340582 (1982-07-01), Kriesel et al.
patent: 4543370 (1985-09-01), Porter et al.
patent: 4661367 (1987-04-01), Forse et al.
patent: 4802924 (1989-02-01), Woznicki et al.
patent: 4880636 (1989-11-01), Franz
patent: 4931286 (1990-06-01), Johnson et al.
patent: 5037797 (1991-08-01), Kunamoto et al.
patent: 5248516 (1993-09-01), Wheatley et al.
Remington's Pharmaceutical Sciences, 18th Edition, 1990, Mack Publishing Co., Easton Pa pp. 1671, 1668-69.

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