DX-52-1 compounds and process for preparing the same

Details DX-52-1 compounds and process for preparing the same DX-52-1 compounds and process for preparing the same

1984-05-04

1987-03-17

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544342, C07D48718, C07D49822, A61K 31495

Patent

active

046508694

ABSTRACT:
A compound represented by the formula: ##STR1## wherein R is a hydrogen atom or a lower alkyl group, X is a hydroxymethyl group and Y is a cyano group, and when R is a lower alkyl group, X and Y may combine to form --CH.sub.2 --O--, and salts thereof, process for preparing the same, and an anti-tumor composition containing the same, which is improved in stability in comparison with a starting compound DC-52.

REFERENCES:
Danishefsky, Chem. Abs. 102, 95887f (1984).
Kyowa Chemical Abstracts, vol. 98, 1983, p. 416, No. 86722z.

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