Duodenal and gastric ulcer treatment with oral urogastrone

Details Duodenal and gastric ulcer treatment with oral urogastrone Duodenal and gastric ulcer treatment with oral urogastrone

1987-07-02

1989-04-11

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514925, 514926, A61K 3724

Patent

active

048206903

ABSTRACT:
Pharmaceutical compositions for oral administration comprise human urogastrone or a urogastrone fragment as active ingredient and such an active ingredient may be used for the manufacture of a medicament for promoting healing of a damaged alimentary tract.

REFERENCES:
patent: 3883497 (1975-05-01), Gregory et al.
patent: 4032633 (1977-06-01), Gregory et al.
patent: 4035485 (1977-07-01), Gregory et al.
HORI, et al., Effect of Bile Salts and Oil-in Water Emulsions on the Intestinal Absorption of Urogastrone in the Rat, Chem. Pharm. Bull., 25, 1974-1979 (1977).
Luccetti et al., Antiulcer Action of Urogastrone, Boll. Chim. Farm. 112(8) 532 (1973).
Gregory et al., The Identification of Urogastrone in Serum, Saliva and Gastric Juice, Gastronterology, 77, 313-318 (1973).
The Merck Index, 10th Edition p. 3496-7 (1983).
Gregory H., Isolation and Structure of Urogastrone and its Relationship to Epidermal Growth Factor, Nature, 257, 325-327 (1975).

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