Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2006-08-18
2009-11-03
Blanchard, David J. (Department: 1643)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C530S388100, C530S391300, C530S391700, C424S178100, C424S181100, C424S183100
Reexamination Certificate
active
07612181
ABSTRACT:
The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention and/or treatment of acute and chronic inflammatory and other diseases.
REFERENCES:
patent: 4526938 (1985-07-01), Churchill et al.
patent: 4699784 (1987-10-01), Shih et al.
patent: 4816567 (1989-03-01), Cabilly et al.
patent: 4880078 (1989-11-01), Inoune et al.
patent: 4943533 (1990-07-01), Mendelsohn et al.
patent: 4946778 (1990-08-01), Ladner et al.
patent: 4980286 (1990-12-01), Morgan et al.
patent: 5128326 (1992-07-01), Balazs et al.
patent: 5223409 (1993-06-01), Ladner et al.
patent: 5225539 (1993-07-01), Winter
patent: 5258498 (1993-11-01), Huston et al.
patent: 5290540 (1994-03-01), Prince et al.
patent: 5403484 (1995-04-01), Ladner et al.
patent: 5427908 (1995-06-01), Dower et al.
patent: 5500362 (1996-03-01), Robinson et al.
patent: 5516637 (1996-05-01), Huang et al.
patent: 5530101 (1996-06-01), Queen et al.
patent: 5558864 (1996-09-01), Bendig et al.
patent: 5565332 (1996-10-01), Hoogenboom et al.
patent: 5571698 (1996-11-01), Ladner et al.
patent: 5580717 (1996-12-01), Dower et al.
patent: 5585089 (1996-12-01), Queen et al.
patent: 5624821 (1997-04-01), Winter et al.
patent: 5627052 (1997-05-01), Schrader et al.
patent: 5641870 (1997-06-01), Rinderknecht et al.
patent: 5648260 (1997-07-01), Winter et al.
patent: 5658727 (1997-08-01), Barbas et al.
patent: 5677171 (1997-10-01), Hudziak et al.
patent: 5679377 (1997-10-01), Bernstein et al.
patent: 5693762 (1997-12-01), Queen et al.
patent: 5698426 (1997-12-01), Huse et al.
patent: 5714350 (1998-02-01), Co et al.
patent: 5714352 (1998-02-01), Jakobovits et al.
patent: 5723323 (1998-03-01), Kauffman et al.
patent: 5733743 (1998-03-01), Johnson et al.
patent: 5736137 (1998-04-01), Anderson et al.
patent: 5750753 (1998-05-01), Kimae et al.
patent: 5766886 (1998-06-01), Studnicka et al.
patent: 5780225 (1998-07-01), Wigler et al.
patent: 5814476 (1998-09-01), Kauffman et al.
patent: 5817483 (1998-10-01), Kauffman et al.
patent: 5821047 (1998-10-01), Garrard et al.
patent: 5824514 (1998-10-01), Kauffman et al.
patent: 5855913 (1999-01-01), Hanes et al.
patent: 5874064 (1999-02-01), Edwards et al.
patent: 5891996 (1999-04-01), Mateo de Acosta del Rio et al.
patent: 5912015 (1999-06-01), Bernstein et al.
patent: 5916597 (1999-06-01), Lee et al.
patent: 5916771 (1999-06-01), Hori et al.
patent: 5934272 (1999-08-01), Lloyd et al.
patent: 5939598 (1999-08-01), Kucherlapati et al.
patent: 5969108 (1999-10-01), McCafferty et al.
patent: 5976862 (1999-11-01), Kauffman et al.
patent: 5985309 (1999-11-01), Edwards et al.
patent: 6066719 (2000-05-01), Zapata
patent: 6214984 (2001-04-01), Zapata
patent: 2002/0004587 (2002-01-01), Miller et al.
patent: 2002/0127231 (2002-09-01), Schneck et al.
patent: 2002/0136719 (2002-09-01), Shenoy et al.
patent: WO 90/02809 (1990-03-01), None
patent: WO 90/14424 (1990-11-01), None
patent: WO 90/14430 (1990-11-01), None
patent: WO 90/14443 (1990-11-01), None
patent: WO 91/55548 (1991-05-01), None
patent: WO 91/09967 (1991-07-01), None
patent: WO 91/10737 (1991-07-01), None
patent: WO 91/10741 (1991-07-01), None
patent: WO 91/17271 (1991-11-01), None
patent: WO 92/01047 (1992-01-01), None
patent: WO 92/02551 (1992-02-01), None
patent: WO 92/03461 (1992-03-01), None
patent: WO 92/09690 (1992-06-01), None
patent: WO 92/11272 (1992-07-01), None
patent: WO 92/15679 (1992-09-01), None
patent: WO 92/18619 (1992-10-01), None
patent: WO 92/19244 (1992-11-01), None
patent: WO 92/20791 (1992-11-01), None
patent: WO 92/22324 (1992-12-01), None
patent: WO 93/01288 (1993-01-01), None
patent: WO 93/11236 (1993-06-01), None
patent: WO 94/02602 (1994-02-01), None
patent: WO 94/18219 (1994-08-01), None
patent: WO 95/15982 (1995-06-01), None
patent: WO 95/20045 (1995-07-01), None
patent: WO 95/20401 (1995-08-01), None
patent: WO 95/24918 (1995-11-01), None
patent: WO 96/20698 (1996-07-01), None
patent: WO 96/33735 (1996-10-01), None
patent: WO 96/34096 (1996-10-01), None
patent: WO 96/40210 (1996-12-01), None
patent: WO 97/20032 (1997-06-01), None
patent: WO 97/29131 (1997-08-01), None
patent: WO 97/32572 (1997-09-01), None
patent: WO 97/44013 (1997-11-01), None
patent: WO 98/16654 (1998-04-01), None
patent: WO 98/24893 (1998-06-01), None
patent: WO 98/31346 (1998-07-01), None
patent: WO 98/31700 (1998-07-01), None
patent: WO 98/50433 (1998-11-01), None
patent: WO 99/06834 (1999-02-01), None
patent: WO 99/15154 (1999-04-01), None
patent: WO 99/20253 (1999-04-01), None
patent: WO 99/23221 (1999-05-01), None
patent: WO 99/25044 (1999-05-01), None
patent: WO 99/45031 (1999-09-01), None
patent: WO 99/53049 (1999-10-01), None
patent: WO 99/54342 (1999-10-01), None
patent: WO 99/66903 (1999-12-01), None
patent: WO 00/09560 (2000-02-01), None
patent: WO 00/37504 (2000-06-01), None
patent: WO 00/56772 (2000-09-01), None
patent: WO 01/58956 (2001-08-01), None
patent: WO 01/62931 (2001-08-01), None
patent: WO 01/77342 (2001-10-01), None
patent: WO 01/77342 (2001-10-01), None
patent: WO 01/83525 (2001-11-01), None
patent: WO 01/88138 (2001-11-01), None
patent: WO 02/02773 (2002-01-01), None
patent: WO 02/072636 (2002-09-01), None
patent: WO 02/097048 (2002-12-01), None
patent: WO 03/016466 (2003-02-01), None
patent: WO 03/035835 (2003-05-01), None
patent: WO 2004/078140 (2004-09-01), None
patent: WO 2005/100584 (2005-10-01), None
Li, Q., Carr, A.L., Donald, E.J., Skitzki, J.J., Okuyama, R., Stoolman, L.M., and Chang, A.E. Synergistic effects of IL-12 and IL-18 in skewing tumor-reactive T-cell responses towards a type I pattern. Cancer Research, 2005. vol. 65, pp. 1063-1070.
Margolin, A.L. and Navia, M.A. Protein crystals as novel catalytic materials. Angew. Chem. Int. Ed., 2001. vol. 40, pp. 2204-2222.
Ames et al., Journal of Immunological Methods, (1995), “Conversion of murine Fabs isolated from a combinatorial phage display to full length immunoglobulins.” 184: 177-186.
Aoki et al., Journal of the American College of Cardiology, (2005), “Endothelial Progenitor Cell Capture by Stents Coated With Antiobody Against CD34” 45(10): 1574-1579.
Arancio O. et al., EMBO Journal, (2004), “RAGE potentiates AB-induced perturbation of neurol function in transgenic mice” 23: 4096-4105.
Arndt, M. et al., Methods in Molecular Biology, (2003), “Bispecific Diabodies for Cancer Therapy” 207: 305-321.
Azzazy H. et al., Clinical Biochemistry, (2002), “Phage display technology: clinical applications and recent innovations” 35: 425-445.
Babcock, J.S. et al, Proc. Natl. Acad. Sci. USA, (1996), “A novel strategy for generating monoclonal antibodies from single, isolated lymphocytes producing antibodies of defined specificities” 93: 7843-7848.
Barbas, C.F. et al., Proc. Natl. Acad. Sci. USA, (1991), “Assembly of combinatorial antibody libraries on phage surfaces: The gene III site” 88: 7978-7982.
Barbas, C.F. et al., Proc. Natl. Acad. Sci. USA, (1994), “In vitro evolution of a neutralizing human antibody to human immunodeficiency virus type 1 to enhance affinity and broaden strain cross-reactivity” 91: 3809-3813.
Dickson, B.J. et al., Science, (2002), “Molecular Mechanisms of Axon Guidance” 298: 1959-1964.
Better et al. Science, (1988), “Secretion of an Active Chimeric Antibody Fragment” 240: 1041-1043.
Biewanga et al. Clinical Exp. Immunology, (1983), “IgA1 half moleculed in human multiple myeloma and the in vitro production of similar fragments from intact IgA1 molecules” 51: 395-400.
Bird et al. Science, (1988), “Single- Chain Antigen-Binding Proteins”, 242: 423-426.
Bornemann KD et al., American Journal of pathology, (2001), “AB-Induced Inflammatory Processes in Microglia Cells of APP23 Transgenic Mice”, 158(1): 63-73.
Boyce et al., Journal of Experimental Medicine, (2005), “No audible wheezing: nuggets and conundrums from mouse asthma models”, 201(12): 1869-1873.
Brand DD., Comparative Medicine, (20
Dixon Richard W.
Ghayur Tariq
Salfeld Jochen G.
Wu Chengbin
Abbott Laboratories
Blanchard David J.
Gussow Anne M.
Seshadri Tara
Yankwich & Associates P.C.
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