Dual pharmacophores—PDE4-muscarinic antagonistics

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S253040, C514S303000, C540S575000, C544S362000, C546S119000

Reexamination Certificate

active

08084449

ABSTRACT:
The present invention is directed to novel compounds of Formula (I) and pharmaceutically acceptable salts thereof,pharmaceutical compositions and their use as dual chromaphores having inhibitory activity against PDE4 and muscarinic acetylcholine receptors (mAChRs), and thus being useful for treating respiratory diseases.

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