Dual isotope assays

Details Dual isotope assays Dual isotope assays

1980-01-30

1982-06-01

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

23230B, G01N 3356, G01T 100, G01N 3360

Patent

active

043327842

ABSTRACT:
Dual isotope assays for thyroid function are performed by carrying out a radio-immunoassay for two of thyroxine (T4), tri-iodothyronine (T3), thyroid stimulating hormone (TSH), and thyroxine binding globulin (TBG) wherein a version of one of the thyroid components, preferably T4 or T3 is labelled with Selenium-75 and the version of the other thyroid component is labelled with a different radionuclide, preferably Iodine-125.

REFERENCES:
patent: 3952091 (1976-04-01), Grunberg et al.
patent: 4016250 (1977-04-01), Saxena
patent: 4115065 (1978-09-01), Bayly et al.
patent: 4225576 (1980-09-01), Denning et al.
Brown et al.; J. Nucl. Med., 18, #3, 300-304, 1977.
Girgis et al.; Nuclear Science Abstracts, vol. 26, #3, Feb. 15, 1972, Abstract 4672.
Mitsuma et al.; Biochem. Biophys. Res. Comm., vol. 46, #6, 2107-2113, 1972.

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