Dual components antiplaque dentifrice compositions

Details Dual components antiplaque dentifrice compositions Dual components antiplaque dentifrice compositions

1998-01-12

1998-12-01

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Dentifrices

424 52, 424 57, A61K 716, A61K 718

Patent

active

058434062

ABSTRACT:
A dual component antiplaque dentifrice composition in which the first component is an extrudible dentifrice composition containing a nonionic antibacterial agent in which calcium salts are absent and the second component is an extrudable dentifrice composition containing a calcium salt wherein maximum antibacterial agent uptake by dental tissue is achieved when the components and are physically separated prior to use and are mixed upon application to dental tissue.

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Tahmassebl et al Caries Res. 28(4):272-276 Effect of a Calcium Carbonate-Based Toothpaste With 0.3% Triclofan on pH Changes in Dental Plaque in vivo, 1994.

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