DTEF-1 isoforms and uses thereof

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Primate cell – per se

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435243, 4353201, 435325, 536 235, C12N 510, C12N 100, C12N 1512, C12N 1563

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active

057767769

ABSTRACT:
Transcription enhancer factor 1 (TEF-1) gene family polypeptides are described. In particular, DTEF-1 isoforms are provided. The isoforms may be used for the differential regulation of genes which contain upstream TEF-1 binding sites. Thus, TEF-1 family polypeptides may be used to directly or indirectly regulate transcription of genes linked to the TEF-1 binding sites, such as genes which are expressed in cardiac tissue.

REFERENCES:
Xiao et al, Cell, May 17, 1991, vol. 65 : pp. 551-568.
Ngo et al, The Protein Folding Problem and Tertiary Structure Prediction, 1994, Mertz et al (Eds), Birkhauser, Boston, MA, pp. 433 and 492-495.

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