Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Matrices
Patent
1995-12-19
1999-10-26
Myers, Carla J.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Matrices
424486, 424488, 424489, 424502, 435 6, 435 912, 435 915, 435 9151, A61K 914, A61K 950, C12Q 168, C12P 1934
Patent
active
059723866
ABSTRACT:
The present invention provides a dry solid medium for storing a sample of a genetic material, including RNA and DNA, in a form suitable for subsequent analysis. The dry solid medium of the invention includes a dry solid matrix and a composition including a protein denaturing agent, and a chelating agent. The dry solid medium can further include a component which functions in subsequent analysis of the genetic material using, for example, PCR, reverse transcriptase initiated PCR, LCR, RFLP, or genetic hybridization. A component for subsequent analysis includes, for example, a nucleotide sequences such as a primer, DNA or RNA probe, and a target sequence stabilizer. The dry solid medium can also include a retaining agent to enhance retention of a component for subsequent analysis. The invention also provides methods for using the dry solid medium of the invention. The dry solid media and methods of use thereof are particularly suited for use in automated systems.
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Flinders Technologies Pty, Ltd.
Johannsen Diana
Myers Carla J.
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