Dry radioimmunoassay test composition containing stabilized labe

Details Dry radioimmunoassay test composition containing stabilized labe Dry radioimmunoassay test composition containing stabilized labe

1979-09-12

1982-01-12

Padgett, Benjamin R.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

23230B, 422 61, 424 12, G01N 3348, G01T 100, B65D 7100

Patent

active

043105041

ABSTRACT:
A dry radioimmunoassay test composition comprising a mixture of a radiolabelled form of a ligand, i.e., a hapten or an antigen, an antibody for the ligand, and a heavy metal cation, e.g., cupric ion, to inhibit the complex-forming reaction between the radiolabelled ligand and the antibody. A method for preparing the dry test composition is also provided. In use in a radioimmunoassay, the dry test composition is reconstituted with an aqueous liquid and combined with a test sample and a chelating agent to bind the heavy metal cation, permitting reaction among any ligand present in the sample, the radiolabelled ligand, and the antibody. A test kit for performing such radioimmunoassay is also provided.

REFERENCES:
patent: 4017597 (1977-04-01), Reynolds

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