Dry compositions for preparing submicron emulsions

Details Dry compositions for preparing submicron emulsions Dry compositions for preparing submicron emulsions

1993-02-12

1995-12-05

Kishore, Gollamudi S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

514937, 514938, 514939, 514943, 264 41, 264 43, A61K 9127

Patent

active

054727065

ABSTRACT:
The present invention relates to dry, stable compositions which can be reconstituted to form pharmaceutical or cosmetic emulsions, and to methods for making such compositions. An emulsion is formed from about 0.2 to 25 weight percent of a first component of an oil, about 0.1 to 5 weight percent of a second component of an emulsifier, about 0.25 to 25 weight percent of a cryoprotectant of an amino compound, such as one or more amino acids, peptides or protein hydrolysates, and an aqueous component, wherein the amino compound is present in an amount that is equal to or greater than that of the first component. Optionally, a co-emulsifier, a suspension agent, a preservative, an antioxidant and a drug can be added to these emulsions. Thereafter, the emulsion is lyophilized to form dry compositions that have from about 40 to about 90 weight percent of the amino compound; from about 0.1 to about 20 weight percent of the emulsifier; and from about 0.2 to about 40 weight percent of the oily component. By combining the dry composition with an appropriate quantity of an aqueous liquid, the composition is reformed as an oil-in-water emulsion.

REFERENCES:
patent: 4178695 (1979-12-01), Erbeia
patent: 4616047 (1986-10-01), Lafon
patent: 4647586 (1987-03-01), Mizushima et al.
patent: 5004756 (1991-04-01), Ogawa et al.

Affiliated with

Also associated with

Rating

Dry compositions for preparing submicron emulsions does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Dry compositions for preparing submicron emulsions, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Dry compositions for preparing submicron emulsions will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1372328