Drugs for topical application of sex steroids in the treatment o

Details Drugs for topical application of sex steroids in the treatment o Drugs for topical application of sex steroids in the treatment o

1992-07-16

1994-04-05

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514169, 514177, 514178, 514912, 514914, A61K 31565, A61K 3157

Patent

active

RE0345784

ABSTRACT:
A topical drug application for the alleviation of kerato-conjunctivitis sicca (dry eye syndrome) is comprised of a solution of sex steroids or their derivatives suspended or dissolved in a vehicle, and the method of preparation and application of the same. In the preferred embodiments, the sex steroid consists essentially of conjugated estrogen in a lipid vehicle or a derivative of estrogen known as 17 beta-Estradiol 3-phosphate disodium dissolved in an aqueous vehicle having a pH of between 6 and 8.

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