Drugs for chronic pains

Details Drugs for chronic pains Drugs for chronic pains

2007-04-03

2007-04-03

McKane, Joseph K. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S506000, C546S335000, C560S019000, C560S125000, C560S128000, C560S016000, C560S147000, C564S241000

Reexamination Certificate

active

10480805

ABSTRACT:
Nitro-oxyderivative compounds or salts thereof having the following general formula (I): A—(B)b0—(C)c0—NO2wherein: c0 is an integer and is 0 or 1, b0 is an integer and is 0 or 1, A=R—T1—, wherein R is the radical of an analgesic drug for the chronic pain, in particular for the neuropathic pain; B is such that its precursor is selected from anminoacids, hydroxyacids, polyalcohols, compounds containing at least one acid function; C is a bivalent radical containing an aliphatic, heterocyclic or aromatic radical.

REFERENCES:
patent: 5844696 (1998-12-01), Masia et al.
patent: 6187338 (2001-02-01), Caruso et al.
patent: 95/09831 (1995-04-01), None
patent: WO 95 30641 (1995-11-01), None
patent: WO 96 19233 (1996-06-01), None
patent: 97/16405 (1997-05-01), None
patent: WO 98 09948 (1998-03-01), None
patent: WO 00 06567 (2000-02-01), None
patent: WO 00 44705 (2000-08-01), None
patent: WO 00 54773 (2000-09-01), None
patent: WO 00 66582 (2000-11-01), None
patent: 00/76958 (2000-12-01), None
patent: 01/12584 (2001-02-01), None
patent: WO 01 83490 (2001-11-01), None
patent: WO 02 30866 (2002-04-01), None
patent: WO 02 30867 (2002-04-01), None
Radomski et al., “The anti-aggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide”, BR. J. Pharmac. (1987), 92, pp. 639-646.
Bennett et al., “A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man”, Pain, 33 (1988), pp. 87-107.
Xu et al., “Chronic pain-related syndrome in rats after ischemic spinal cord lesion: a possible animal model for pain in patients with spinal cord injury” Pain, 48 (1992), pp. 279-290.
Hao et al., “Treatment of a chronic allodynia-like response in spinally injured rats: effects of systemically administered excitatory amino acid receptor antagonists”, Pain, 66, (1996), pp. 279-285.
Martindale, The Extra Pharmacopoeia 13thEdition, p. 374.

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