Drugs containing a glycosylated interleukin-2

Details Drugs containing a glycosylated interleukin-2 Drugs containing a glycosylated interleukin-2

1993-11-16

1995-05-23

Russel, Jeffrey E.

Drug, bio-affecting and body treating compositions

Lymphokine

Interleukin

435 6952, 530351, 530416, 530417, A61K 3702, C07K 320, C07K 322, C07K 1514

Patent

active

054179700

ABSTRACT:
An interleukin-2 preparation suitable for pharmaceutical purposes, consisting essentially of disialilated glycosylated interleukin-2, monosialilated glycosylated interleukin-2, or a mixture thereof, and substantially free of organic solvents, is isolated from recombinant CHO cells transformed with a vector containing a DNA sequence coding for a natural precursor of human interleukin-2, and is purified by a multi-step process.

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patent: 5217881 (1993-06-01), Park
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