Drug targets in Candida albicans

Details Drug targets in Candida albicans Drug targets in Candida albicans

2006-10-24

2006-10-24

Navarro, Mark (Department: 1645)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S023700, C435S252300, C435S320100

Reexamination Certificate

active

07125970

ABSTRACT:
The present invention is concerned with the identification of genes or functional fragments thereof fromCandida albicanswhich are critical for growth and cell division and which genes may be used as selective drug targets to treatCandida albicansassociated infections. Novel nucleic acid sequences fromCandida albicansare also provided and which encode the polypeptides which are critical for growth ofCandida albicans. Methods for the identification of anti-fungal compounds which inhibit fungal or yeast growth are also contemplated.

REFERENCES:
patent: 5576428 (1996-11-01), Butler et al.
patent: 2005/0042646 (2005-02-01), Davidson et al.
patent: 2005/0147694 (2005-07-01), Brewer
Daly et al. Gene, vol. 187, No. 2, pp. 151-158, 1997.
NIH, Gene Therapy Report, Dec. 1995.

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