Drug sensitivity measuring method

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism

Reexamination Certificate

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C435S287100

Reexamination Certificate

active

10221800

ABSTRACT:
Disclosed herein is a method for determining the drug sensitivity of a microbe which comprises pouring a microbial suspension into each of the compartments or wells at a position which is in the vicinity of an electrode for measuring dissolved oxygen concentration, measuring current from each electrode at a second time interval for a third time period, each time is obtained based upon each of the measured currents at which the maximum current is obtained, obtaining each current value within a fourth time period which starts from the time at which the maximum current is obtained, detecting drug sensitivity based upon the variation condition of each current value during the fourth time period. The method allows rapid drug susceptibility measurements.

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Abu-Amero et al. (Applied and Environmental Microbiology, vol. 62, No. 9, pp. 3107-3111).
Wodnicka et al. Journal of Biomolecular Screening, 2000. vol. 5, No. 3, pp. 141-152.

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