Drug salts

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514 23, 514 53, 530322, 536 71, 536 72, 536 138, A61K 3170, A61K 3816, C07H 1708, C07K 900

Patent

active

060778229

ABSTRACT:
It has been found that sugar acid salts represent beneficial controlled release forms for basic organic drug compounds. Examples of appropriate salts include mono, di, oligo and polysaccharide poly-O-sulphonic acid salts of antibiotics such as tetracyclins and aminoglycosides.

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H. Yoshikawa et al.; "Development of Bifunctional Delivery System for Selective Transfer of Drug into Lymphatics Via Enteral Route and Transfer Mechanism"; J. Pharm. Dyn.; 5,S-69 (1982).
D. Mihai et al.; "Macromolecular Drug Conjugates Propranolol-Cation Exchangers Drug Delivery Systems"; Cellulose Chemistry and Technology; 27, pp. 393-403 (1993).
K. Ochi et al.; "Crystalline Salts of Sucrose Octasulfate"; Chem. Pharm. Bull.; vol. 28; pp. 638-641 (1980).
J. Jesper et al.; "Brief Report--In Vitro Susceptibility of Campylobacter Pyloridis to Cimetidine, Sucralfate, Bismuth and Sixteen Antibiotics"; Acta. path. microbiol. immunol. scand.; Sect. B, 95; pp. 147-149 (1987).

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