Drug preparation comprising α-lipoic acid, ambroxol...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Reexamination Certificate

active

07858655

ABSTRACT:
The present invention concerns the use of Provided is a drug composition and a method for using the composition for the prevention and the therapy of neurodegenerative diseases. The combination comprises at least two of the following substances: α-lipoic acid; ambroxol and one or several inhibitor(s) of the angiotension-converting enzyme (ACE).

REFERENCES:
patent: 2002/0177558 (2002-11-01), Meyerhoff et al.
patent: WO 02/096398 (2002-12-01), None
patent: WO 02/096414 (2002-12-01), None
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Ravati, Alexander, Vera Junker, Maria Kouklei, Barbara Ahlemeyer, Carsten Culmsee, and Josef Krieglstein, “Enalapril And Moexipril Protect From Free Radical-Induced Neuronal Damage In Vitro And Reduce Ischemic Brain Injury In Mice And Rats,”European Journal Of Pharmacology, 1999, pp. 21-33, vol. 373.
Stoll, S., A. Rostock, R. Bartsch, E. Korn, A. Meichelböock, and W.E. Müller, “The Potent Free Radical Scavenger α-Lipoic Acid Improves Cognition In Rodents,”Annals New York Academy Of Sciences, 1994, pp. 122-128.
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