Drug preparation applicable to oral mucosa

Details Drug preparation applicable to oral mucosa Drug preparation applicable to oral mucosa

1990-01-31

1992-08-11

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424 7808, 424 7831, 424484, 424486, 424487, 424488, 514 54, 514 57, 514777, 514778, 514784, 514785, 514944, 514945, 514953, 514955, A61F 1302, A61K 3178, A61K 970, A61L 1516

Patent

active

051377292

ABSTRACT:
A drug preparation applicable to the oral mucosa is disclosed, comprising a soft adhesive film containing a systemic drug, the adhesive film comprising a homogeneous mixture comprising a vinyl acetate homopolymer, an acrylic acid polymer, and a cellulose derivative capable of being dissolved in or swollen with water and a lower alcohol. The drug preparation is less causative of an adverse feeling in the oral cavity on use, excellent in shape retention on water absorption, and adhesive to the oral mucosa for an extended period of time, thereby achieving a stable administration of a systemic drug for a long time.

REFERENCES:
patent: 4666441 (1987-05-01), Andriola et al.
patent: 4921695 (1990-05-01), Babaian et al.
Chemical Abstracts, vol. 99, No. 22, Abstract No. 181420z, 1983.
Chemical Abstracts, vol. 83, Abstract No. 103302t, 1975.

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