Drug for treatment of gastric and duodenal peptic ulcer disease

Details Drug for treatment of gastric and duodenal peptic ulcer disease Drug for treatment of gastric and duodenal peptic ulcer disease

1990-05-23

1992-05-12

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514461, A61K 3140, A61K 3134

Patent

active

051128500

ABSTRACT:
A composition for the treatment of gastric and duodenal peptic ulcer disease which is a combination of trapencaine and rantidine is disclosed.

REFERENCES:
Babulova, A., et al., "Action of Pentacain on Gastric Acid Secretion", Agents and Actions (1988), vol. 23, pp. 286-288.
Toson, G. et al., "Effects of Ranitidine on Gastric Lesions and Antiinflammatory Actions of Aspirin and Indomethacin in the Rat", Current Therapeutic Research (1985), vol. 38, pp. 855-862.
Schotborgh, R. H., et al., "Combination Therapy of Sucralfate and Cimetidine, Compared with Sucralfate Monotherapy, in Patients with Peptic Reflux Esophagitis", American Journal of Medicine, 86 (Suppl 6A), 77-80, (1989).
Ranitidine, Histamine H.sub.2, Receptor Gastric Secretion in Heidenhain Pouch Dogs, Folia pharmacol. Japon, 78, 539-547 (1981).
New Drugs for Peptic Ulcer by David A. Henry in The Medical Journal of Australia, Sep. 1, 1984, pp. 303, 304.
Peptic Ulcer Disease, Cytoprotection and Prostaglandins by K. Lauritsen and J. Rask-Madsen, Arch. Intern Med., vol. 150, Mar. 1990, p. 695.
Chem Abst, 108:216208v (1988). Babulova et al.
Chem Abst, 104:61855v (1986). Toson et al.

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