Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Reexamination Certificate
2003-04-26
2008-10-21
Sheikh, Humera N (Department: 1618)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
C424S400000, C424S423000
Reexamination Certificate
active
07438925
ABSTRACT:
Drug eluting coating compositions are composed of at least one therapeutic agent dispersed in modified, biologically active binders. The therapeutic agents included in the coating composition are paclitaxel, sirolimus, tacrolimus, everolimus, actinomycin-D, dexamethasone, mycophenolic acid, cyclosporins, estradiol, and derivatives and analogs thereof. These therapeutic agents are applied to the surface of the medical device by a modified, biologically active binders. By using these biologically active binders, the therapeutic agents can be applied to at least one surface of a medical implant without using inert polymer carriers.
REFERENCES:
patent: 3663288 (1972-05-01), Miller
patent: 4613665 (1986-09-01), Larm
patent: 4634762 (1987-01-01), Feijen et al.
patent: 4676975 (1987-06-01), McGary et al.
patent: 4871357 (1989-10-01), Hsu et al.
patent: 5047020 (1991-09-01), Hsu
patent: 5061738 (1991-10-01), Solomon et al.
patent: 5102401 (1992-04-01), Lambert et al.
patent: 5112457 (1992-05-01), Marchant
patent: 5288711 (1994-02-01), Mitchell et al.
patent: 5356433 (1994-10-01), Rowland et al.
patent: 5447724 (1995-09-01), Helmus et al.
patent: 5455040 (1995-10-01), Marchant
patent: 5464650 (1995-11-01), Berg et al.
patent: 5496832 (1996-03-01), Armstrong
patent: 5525348 (1996-06-01), Whitbourne et al.
patent: 5609629 (1997-03-01), Fearnot et al.
patent: 5665728 (1997-09-01), Morris et al.
patent: 5716981 (1998-02-01), Hunter et al.
patent: 5824049 (1998-10-01), Ragheb et al.
patent: 5837313 (1998-11-01), Ding
patent: 5919762 (1999-07-01), Schweden et al.
patent: 5980972 (1999-11-01), Ding
patent: 6120536 (2000-09-01), Ding et al.
patent: 6179817 (2001-01-01), Zhong
patent: 6231600 (2001-05-01), Zhong
patent: 6251136 (2001-06-01), Guruwaiya et al.
patent: 6258121 (2001-07-01), Yang et al.
patent: 6273913 (2001-08-01), Wright et al.
patent: 6299604 (2001-10-01), Ragheb et al.
patent: 6306166 (2001-10-01), Barry et al.
patent: 6309660 (2001-10-01), Hsu et al.
patent: 6316018 (2001-11-01), Ding et al.
patent: 6335029 (2002-01-01), Kamath et al.
patent: 6344035 (2002-02-01), Chudzik et al.
patent: 6749626 (2004-06-01), Bhat et al.
patent: 2001/0007083 (2001-07-01), Roorda
patent: 2002/0133183 (2002-09-01), Lentz et al.
patent: WO9836784 (1998-08-01), None
patent: WO02062335 (2002-08-01), None
Mehran R et al. Circulation 1990;100:1872-1878.
Schwartz RS. J Invas cardiol 1996;8:386-387.
Rogers C et al. Circulation 1993;88:1215-1221.
Serruys PW et al. N Eng J Med 1991;324:13-17.
Schatz RA et al. Circulation 1991;83:148-161.
Lablanche JM et al. Eur Heart J 1996;17:1373-1380.
Goods CM et al. Circulation 1996;93:1803-1808.
Mak KH et al. J Am Coll Cardiol 1996;27:494-503.
Hermanson GT et al. Immobilized Affinity Ligand Techniques. 1992;195-202. Academic Press.
Jozefonvicz et al.; Blood-Contacting Polymers; Polymeric Biomaterials; 1994; pp. 349-371; Marcel Dekker, Inc.; New York, New York.
Hsu; Biocompatibility in Cardiopulmonary Bypass; Journal of Cardiothoracic and Vascular Anesthesis; May 1997; pp. 376-382; vol. 11, No. 3.
van der Giessen et al.; Marked Inflammatory Sequelae to Implantation of Biodegradable and Nonbiodegradable Polymers in Porcine Coronary Arteries; Circulation; Oct. 1, 1996; pp. 1690-1697; vol. 94, No. 7.
Biovention Holdings Ltd.
Sheikh Humera N
Steptoe & Johnson LLP
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