Drug efflux pump inhibitor

Details Drug efflux pump inhibitor Drug efflux pump inhibitor

2006-06-06

2006-06-06

Rao, Deepak (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S248000, C514S258100, C514S300000, C514S312000, C544S116000, C544S235000, C544S236000, C544S282000, C546S122000, C546S153000, C546S155000, C546S156000

Reexamination Certificate

active

07056917

ABSTRACT:
A medicament for preventive and/or therapeutic treatment of a microbial infection which comprises as an active ingredient a compound represented by the following general formula (I):wherein, R1and R2represent hydrogen atom, a halogen atom, hydroxyl group or the like, W1represents —CH═CH—, —CH2O—, —CH2CH2— or the like; R3represents hydrogen atom, a halogen atom, hydroxyl group or an amino group; R4represents hydrogen atom, a group of —OZ0-4R5(Z0-4represents an alkylene group, a fluorine-substituted alkylene group or a single bond, and R5represents a cyclic alkyl group, an aryl group or the like); W2represents a single bond or —C(R8)═C(R9)— (R8and R9represent hydrogen atom, a halogen atom, a lower alkyl group or the like, Q represents an acidic group, but W2and Q may together form vinylidenethiazolidinedione or an equivalent heterocyclic ring; m and n represent an integer of 0 to 2, and q represents an integer of 0 to 3.

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