Drug delivery devices manufactured from poly(orthoesters) and po

Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...

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424 20, 128260, A61K 922, A61K 956, A61M 3700

Patent

active

040937097

ABSTRACT:
The invention concerns orthoester and orthocarbonate polymers having a repeating mer comprising a hydrocarbon radical and a symmetrical dioxycarbon unit of the general formula: ##STR1## WHEREIN R.sub.1 is a multivalent hydrocarbon radical, R.sub.2 and R.sub.3 are hydrocarbon radicals with at least one of R.sub.2 or R.sub.3 bonded to the dioxycarbon through an oxygen linkage, and which polymers are synthesized by reacting a polyol with an orthoester or orthocarbonate. The polymers are useful for making articles of manufacture, including devices and coatings for delivering beneficial agents.

REFERENCES:
patent: 3887699 (1975-06-01), Yolles
patent: 3960150 (1977-06-01), Hussain
patent: 4001388 (1977-01-01), Shell
patent: 4014987 (1977-03-01), Heller

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