Drug delivery devices

Details Drug delivery devices Drug delivery devices

1989-08-29

1991-05-07

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424435, 424 78, 4241951, 424 58, 514900, A61K 726, A61K 600, A61F 200

Patent

active

050135538

ABSTRACT:
Drug delivery devices and techniques are described for use in treatment of periodontal disease and the like. The delivery device includes benzo (c) phenanthridine alkaloid in a bioerodable and biocompatible material. The alkaloid is slowly released from the bioerodable material in the oral cavity. The bioerodable material may be polymeric and may be natural or synthetic. The delivery device may be inserted subgingivally (e.g., in a periodontal pocket) where the alkaloid is released slowly over a period of days.

REFERENCES:
patent: 4406881 (1983-09-01), Ladanyi
patent: 4515771 (1985-07-01), Fine
patent: 4568535 (1986-02-01), Loesche
patent: 4599228 (1986-07-01), Ladanyi
patent: 4685883 (1987-08-01), Jernberg
patent: 4722948 (1988-02-01), Sanderson
patent: 4764377 (1988-08-01), Goodson
patent: 4780320 (1988-10-01), Baker
Isoquinoline Alkaloids in Local Periodontal Disease Therapy, Cerna et al., 1984, pp. 159-162.

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