Drug delivery device, its preparation and use

Details Drug delivery device, its preparation and use Drug delivery device, its preparation and use

1987-06-02

1988-11-15

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

424456, 424443, 424445, A61F 1300

Patent

active

047848570

ABSTRACT:
A device suitable for the topical administration of a pharmacologically active agent to an animal is described. The device comprises an active agent impermeable barrier layer, a reservoir containing the active agent which is in contact with the inner surface of the barrier layer and a removable protector layer in contact with the other surface of the reservoir. The reservoir comprises a fibrous mat into which the pharmacologically active agent is incorporated either by dissolving in the polymer forming the mat or by impregnation of a preformed mat. Alternative forms of the reservoir comprise a fibre mat coated on a skin contacting surface with a pressure sensitive adhesive and a fibre mat contained within a gel matrix. The device may be used to deliver nitroglycerin, oxybutynin or phenazocine transdermally.

REFERENCES:
patent: 3287222 (1966-11-01), Larde et al.
patent: 3875300 (1975-04-01), Homm et al.
patent: 4136145 (1979-01-01), Fuchs et al.
patent: 4136162 (1979-01-01), Fuchs et al.

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