Drug delivery device containing neuraminidase inhibitor and...

Details Drug delivery device containing neuraminidase inhibitor and... Drug delivery device containing neuraminidase inhibitor and...

2007-04-24

2007-04-24

Wilson, James O. (Department: 1621)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

C424S473000

Reexamination Certificate

active

10619720

ABSTRACT:
The present invention provides a dual release solid dosage form containing a first composition that releases a neuraminidase inhibitor, such as oseltamivir, zanamivir, or peramivir, in a controlled manner and a second composition that releases an H1 antagonist in a rapid and/or immediate manner. A wide range of H1 antagonist antihistamines, especially fexofenadine and loratadine, can be used in this device. Particular embodiments of the invention provide osmotic devices having predetermined release profiles. The device is useful for the treatment of respiratory congestion and other viral infection associated symptoms.

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