Surgery – Liquid medicament atomizer or sprayer – Pre-pressurized container holding medicament
Patent
1990-09-11
1993-01-12
Burr, Edgar S.
Surgery
Liquid medicament atomizer or sprayer
Pre-pressurized container holding medicament
12820014, 12820312, 12820323, A61M 1100
Patent
active
051781387
ABSTRACT:
A spacer for delivering a maximum amount of a therapeutic agent to the lungs. The spacer may be connected in the inspiratory line running from a mechanical ventilator or hand held and operated manually by the nonintubated, spontaneously breathing patient or the intubated, spontaneously breathing patient. The spacer includes the following features to maximize dispersion of the agent into the fluid flow: a structure for spraying the therapeutic agent in a retrograde fashion to prevent loss of the therapeutic agent to the expiratory limb of the respiratory circuit; a frustoconical shape that reflects the cone-like pattern of an aerosol spray to minimize impaction of the sprayed agent on the inner surfaces of the spacer; and a baffle to readily mix the fluid with the therapeutic agent and deflect fluid flow along the inner walls of the spacer where the therapeutic agent may otherwise collect.
REFERENCES:
patent: 146730 (1874-01-01), Vickers
patent: 1418182 (1922-05-01), Tabor
patent: 2123353 (1938-07-01), Catt
patent: 2631757 (1953-03-01), Alexander
patent: 2670739 (1954-03-01), McNeill
patent: 2788784 (1957-04-01), Birch et al.
patent: 2872923 (1959-02-01), Birch et al.
patent: 2890697 (1959-06-01), VanSickle
patent: 3012555 (1961-12-01), Meshberg
patent: 3302374 (1967-02-01), Szekely
patent: 3356088 (1967-12-01), Nelson
patent: 3490452 (1970-01-01), Greenfield
patent: 3522806 (1970-08-01), Szekely
patent: 3838686 (1974-10-01), Szekely
patent: 4030492 (1977-06-01), Simbruner
patent: 4470412 (1984-09-01), Nowacki et al.
patent: 4484577 (1984-11-01), Sackner et al.
patent: 4592348 (1986-06-01), Waters, IV et al.
patent: 4598704 (1986-07-01), Bordoni et al.
patent: 4796614 (1989-01-01), Nowacki
patent: 4805609 (1989-02-01), Roberts et al.
patent: 4823784 (1989-04-01), Bordoni et al.
patent: 4852561 (1989-08-01), Sperry
patent: 4926852 (1990-05-01), Zoltan et al.
patent: 4938210 (1990-07-01), Shene
patent: 4940051 (1990-07-01), Lankinen
patent: 4972830 (1990-11-01), Wong
patent: 5025806 (1991-06-01), Palmer
patent: 5078131 (1992-01-01), Foley
Crogan S. J., Bixhop, M. J., Delivery Efficiency of Metered Dose Aerosols Given via Endotracheal Tubes, Anesthesiology 1989; 70:1008-1010.
Minisymposium: Delivery of Aerosoloized Medications Respiratory Care, Oct. 1988, vol. 33, No. 10.
European Patent Application No. 0 275 105, filed Jan. 14, 1988; Inventor: Walker; Title: Airway Adapter.
"Portable Equipment for General Anaesthesia, General Analgesia, and Resuscitation"; The Lancet; Dec. 9, 1961, p. 1290.
Monaghan, 3 pg. brochure on AeroVent Holding Chamber (undated).
"A Comparison of Aerosol Deposition in the Lung from Aerochamber vs. Nebulizer in Patients Receiving Mechanical Ventilation", H. D. Fuller et al. (Am. Rev. Resp. Dis. vol. 137; p. 60, 1988).
"Metered Dose Inhaler Actuator-Adapters: A Comparison of Particle Size and Drug Delivery Through an Endotracheal Tube", Richard P. Larson et al. (Resp. Care Nov. 1989, vol. 34, No. 11, p. 1029).
"Terbutaline Aerosol Given Through Pear Spacer in Acute Severe Asthma", M. D. L. Morgan et al., (British Medical Journal, vol. 285, pp. 849-850, Sep. 25, 1982).
"Deposition of Pressurized Suspension Aerosols Inhaled Through Extension Devices", S. P. Newman et al. (Am. Rev. Resp. Dis. 1981; 124:317-320).
One-page brochure DHD Medical Products showing the DHD NIF-TEE Non-Rebreathing T-Piece and its Family of Accessories (undated).
Marquest Respiratory Catelog, pp. 11-16, and 25-29 Front and Back Covers, and Index, showing Nebulizers and Metered Dose Inhaler Adapter Model #172275 (Copyright 1987).
Instrumentation Industries Inc. Catelog, p. 24, Table of Contents, and Front and Back Covers; 1989-1990 Edition.
Monaghan Medical Corp. Packet, 76 pages, showing the Aerochamber with Mask, the Aerochamber, and Publications Relating to the Aerochamber.
Maslonka Steven R.
Scoles Wade J.
Walstrom Dennis R.
Burr Edgar S.
Raciti Eric P.
LandOfFree
Drug delivery device does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Drug delivery device, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Drug delivery device will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1213630