Drug delivery by polymeric carriers

Details Drug delivery by polymeric carriers Drug delivery by polymeric carriers

1982-06-18

1984-07-17

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

424 9, 424 16, 424 31, 424 32, 424 78, 424 80, 424 81, 424 82, 424 83, A61K 4900, A61K 4300

Patent

active

044605609

ABSTRACT:
Anthracycline cancer drugs are covalently coupled to polymeric particles having a diameter of greater than about 0.5 microns to produce pharmaceutical preparations having enhanced cytostatic activity. The coupling of drugs to polymeric carriers shows increased activity against cancer cells, allows the bound drug to retain its cytostatic activity after repeated uses and shows an increase in activity against drug resistant cells.

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