Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2003-07-31
2010-02-09
Tsang, Cecilia (Department: 1654)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C530S300000
Reexamination Certificate
active
07659241
ABSTRACT:
Compounds and compositions are disclosed in which a Drug unit (D) is linked to a Ligand unit (L). In an exemplary embodiment, the compound is of the formulain-line-formulae description="In-line Formulae" end="lead"?LAa-Ww-Yy-D)p Iain-line-formulae description="In-line Formulae" end="tail"?or a pharmaceutically acceptable salt thereof, where A is a stretcher unit, W is an amino acid unit, Y is a spacer unit, D is of the formulaand a, w, y, p and R2-R10are as disclosed in the specification. Methods for treating cancer, autoimmune disease, and infectious disease using the compounds and compositions of the invention are also disclosed.
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Shioiri et
Doronina Svetlana O.
Senter Peter D.
Toki Brian E.
Bradley Christina
Seattle Genetics Inc.
Townsend and Townsend / and Crew LLP
Tsang Cecilia
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