Drug compositions for local treatment of alopecia areata

Details Drug compositions for local treatment of alopecia areata Drug compositions for local treatment of alopecia areata

1985-01-22

1991-01-15

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ketone doai

514676, 514678, 514682, 514880, 514881, A61K 3112

Patent

active

049854640

ABSTRACT:
A drug composition for the local treatment of alopecia areata and other dermatological diseases is disclosed. The composition contains as an active ingredient an aliphatic, alkoxy or aryl substituted cyclopropenone. Diphenylcyclopropenone is a particularly preferred representative cyclopropenone useful in the context of the present invention.

REFERENCES:
patent: 3366664 (1968-01-01), Andreades
patent: 3657348 (1972-08-01), Tobey
patent: 3787500 (1974-01-01), Tobey
Current Therapy, pp. 599-603, (1984).
Current Therapy, pp. 679-680, 755-757, 662, (1981).
Happel, et al., Acta Dermatovener (Stockholm) 63: 49-52, 1983, Deiphencyprone in the Treatment of Alopecia Areata.
Wilkerson, et al., L. Amer. Acad. Dermatol. 11: 802-807, (Nov. 1984), Diphenylcyclopropenone: Examination for Potential Contaminants, Mechanism of Sensitization, and Photochemical Stability.

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