Drug complex

Details Drug complex Drug complex

2005-01-04

2005-01-04

Wilson, James O. (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C536S018200, C536S051000, C536S112000, C536S123100, C530S300000

Reexamination Certificate

active

06838450

ABSTRACT:
A drug complex characterized in that a residue of a drug compound such as antineoplastic agents and a carboxy(C1-4)alkyldextran polyalcohol obtained by treating a dextran under conditions that enable substantially complete polyalcoholization are bound to each other by means of a spacer comprising an amino acid or a spacer comprising peptide-bonded 2 to 8 amino acids. Said complex is characterized in that it has excellent selectivity to tumorous sites so as to exhibit high antineoplastic activity and also achieves reduced appearance of toxicity.

REFERENCES:
patent: 5688931 (1997-11-01), Nogusa et al.
patent: 5811510 (1998-09-01), Papisov
patent: 6291671 (2001-09-01), Inoue et al.
patent: 6436912 (2002-08-01), Inoue et al.
patent: 0640622 (1995-03-01), None
patent: 0757049 (1997-02-01), None
patent: 59220197 (1984-12-01), None
patent: 5-39306 (1993-02-01), None
patent: 6-87746 (1994-03-01), None
patent: 7-84481 (1995-09-01), None
patent: 9214759 (1992-09-01), None
patent: 9419376 (1994-09-01), None
patent: 9961061 (1999-12-01), None
patent: 0025825 (2000-05-01), None
Abstracts of 10th Meeting of the Japan Society of Drug Delivery System, 279, 1994.
Abstracts of 19th Seminar of Trends in Research and Development, pp. D-9 to D-12, 1995.
Abstracs of. 12th Colloid and Interface Technology Symposium, The Chemical Society of Japan, pp. 51-58, 1995.
An English Language abstract of JP 5-39306 published Feb. 19, 1993.
An English Language abstract of 59-220197 published Dec. 11, 1984.
An English Language abstract of JP 6-87746 publishes Mar. 29, 1994.
An English Language abstract of WO 92/14759 published Sep. 3, 1992.
Abstracts of 9th Annual Meeting of Japanese Society for the Study of Xenobiotics, S-292, 1994 Xenobiotic Metabolism and Disposition, vol. 9 Supplement.

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