Drug combinations containing AZT

Details Drug combinations containing AZT Drug combinations containing AZT

1990-02-27

1992-05-26

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514274, A61K 3170, A61K 31505

Patent

active

051168235

ABSTRACT:
Combinations of 3'-azido-3'-deoxythymidine (AZT) with 5-fluorouracil (FUra) or its precursor 5-fluoro-2'-deoxyuridine (FUDR) or methoxtrexate (MTX) exhibit increased cytotoxicity and increased therapeutic index in treatment of carcinomas.

REFERENCES:
patent: 4724232 (1988-02-01), Rideout et al.
patent: 4833130 (1989-05-01), Rideout et al.
patent: 4857511 (1989-08-01), Rideout et al.
Brunetti et al., Cancer Reserach, vol. 37, No. 3, 860A (1989).
Brunetti et al., Preclinical Pharmacology and Experimental Therapeutics, vol. 30, 595 (Abs. 2369) (1989).
Scanlon et al., Cancer Communications, vol. 1, 269-275 (1989).
Minor et al., Proceedings of Asco, vol. 7, 4 (Abs. No. 16), (1988).
Charakhanian Shahin et al., Aspects Cliniques, p. 283, M.B.P. 368, Jun. 4-9, 1989.

Affiliated with

Also associated with

Rating

Drug combinations containing AZT does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Drug combinations containing AZT, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Drug combinations containing AZT will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-419766