Drug carriers

Details Drug carriers Drug carriers

1994-02-22

1997-07-29

Kishore, Gollamudi S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424489, 424490, 424499, 514937, 514943, A61K 910, A61K 9107, A61K 942

Patent

active

056519915

ABSTRACT:
A drug carrier useful for improved drug delivery upon administration comprising a fat or fatty emulsion as a core and a surface layer thereover wherein the core amounts to 30% to 65% and the surface layer amounts to 35% to 70%. The constituents of the core and surface layer are detailed together with the improved drug delivery obtained. The emulsion has a mean particle diameter less than 100 nm.

REFERENCES:
patent: 4094965 (1978-06-01), Layne et al.
patent: 4384975 (1983-05-01), Fong
patent: 4752485 (1988-06-01), Sharma et al.
patent: 4840799 (1989-06-01), Appelgren et al.
patent: 4914084 (1990-04-01), Ecanow
patent: 4933183 (1990-06-01), Sharma et al.
patent: 5023271 (1991-06-01), Vigne
Ekman, Stig et al., Chemistry and Physics of Lipids, 45 (1987) 13-25.
Ekman Stig et al., Biochimica et Biophysica Acta 921 (1987) 347-355.
Tajima, Shoji et al., Journal of Biological Chemistry 258 (1983) 10073-10083.
Okabe, Hiromitsu, et al., J. Biochem., 104, 141-148 (1988).
Connelly, P.W., Biochimica et Biophysica Acta, 666 (1981) 80-89.
Granot, Esther, Biochimica et Biophysica Acta, 833 (1985) 308-315.
Yokoyama, Shinji, et al., J. Biol. Chem. 260, 1985, 3155-3163.
Nishikawa, Osamu, et al., J. Biochem., 103, 188-194 (1988).
Miller, Kurt W., et al., Biochemistry, 22(2), 1983, 443-451.
Weinberg, Richard B., et al., Atherosclerosis, 44 (1982) 141-152.
Badr, Mervat, et al., Journal of Colloid and Interface Science, 113, 414-420 (1986).
Burrier, Robert E., et al., Biochemistry, 23, 5366-5371 (1984).
Mims, Martha P., et al., Biochemistry, 27, 5290-5295 (1988).
Mims, Martha P., et al., Biochemistry, 25, 474-483 (1986).
Spooner, Paul J.R., Journal of Biological Chemistry, 263, 1444-1453 (1988).
Maranhao, Raul C., Biochimica et Biophysica Acta, 875, 247-255 (1986).
Ginsberg, Geoffrey, et al., Journal of Biological Chemistry, 259, 6667-6673 (1987).
Ginsberg, Geoffrey, et al., Journal of Biological Chemistry, 257, 8216-8227 (1982).
Craig, Iain F., et al., Journal of Biological Chemistry, 257, 330-335 (1982).
Tall, A.R., et al., Biochimica et Biophysica Acta, 487, 145-153 (1977).
Ekman, Stig, et al., Biochimica et Biophysica Acta, 959, 343-348 (1988).
Ekman, Lipids, 22, No. 9, (1987), 657-663.

Affiliated with

Also associated with

Rating

Drug carriers does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Drug carriers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Drug carriers will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-631836