Drug administration

Details Drug administration Drug administration

1984-05-25

1988-05-24

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Lymphokine

424100, 514 2, 514 4, 514 12, 514171, A61K 3900, A61K 3156, A61K 3726

Patent

active

047465085

ABSTRACT:
Compositions and methods useful for the prevention or treatment of a human or animal disorder or for the regulation of a human or animal physiological condition are provided. The compositions used comprise, in admixture, a biologically-effective amount of a drug specific for the disorder or condition and a biocompatible, water-soluble, amphiphilic steroid, other than a natural bile salt, which is capable of increasing drug permeability of the human or animal body surface across which the drug is to be administered, in an amount effective to increase the permeability of the surface to the drug.

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S. Hirai et al., Diabetes, 27(3):296-299 (March, 1978).
S. Hirai et al., Int. J. Pharmaceutics, 9:165-172 (1981).
S. Hirai et al., Int. J. Pharmaceutics, 9:173-184 (1981).

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