Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2008-04-18
2011-10-04
Kosar, Andrew D (Department: 1622)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C544S384000
Reexamination Certificate
active
08030315
ABSTRACT:
The present invention provides a novel heterocyclic compound containing a beta-amino group, a method for preparing the same, and a pharmaceutical composition comprising the same heterocyclic compound or a pharmaceutically acceptable salt thereof as an active ingredient. The heterocyclic compound of the present invention exhibits excellent DPP-IV inhibitory activity and bioavailability and therefore can be useful for the prophylaxis or treatment of DPP-IV-related diseases such as diabetes or obesity.
REFERENCES:
patent: 2004/037169 (2004-05-01), None
patent: 2005/011581 (2005-02-01), None
patent: 2005/056003 (2005-06-01), None
patent: 2005/056541 (2005-06-01), None
patent: 2005/095343 (2005-10-01), None
patent: 2005/121131 (2005-12-01), None
patent: 2005/123685 (2005-12-01), None
patent: WO 2005/123685 (2005-12-01), None
patent: 2006/104997 (2006-10-01), None
Biftu, et al., (3R)-4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2- trifluoroethyl)-1,4-diazepan-2-one, a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes, Bioorganic & Medicinal Chemistry Letters, 2007, 17:49-52.
Coumar, et al., 3-[2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-3-methyl-butyramide analogues as selective DPP-IV inhibitors for the treatment of type-II diabetes, Bioorganic & Medicinal Chemistry Letters, 2007, 17:1274-1279.
Choi Song-Hyen
Jang Ji Myun
Kim Hadong
Kim Hae-Sun
Kim Heung Jae
Dong-A Pharm. Co., Ltd.
Kosar Andrew D
Leeser Erich A
Lucas & Mercanti LLP
LandOfFree
DPP-IV inhibitor including beta-amino group, preparation... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with DPP-IV inhibitor including beta-amino group, preparation..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and DPP-IV inhibitor including beta-amino group, preparation... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4284908