Doxycycline metal complex in a solid dosage form

Details Doxycycline metal complex in a solid dosage form Doxycycline metal complex in a solid dosage form

2004-07-22

2009-02-03

Tran, S. (Department: 1618)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Food or edible as carrier for pharmaceutical

C424S464000, C424S465000, C424S489000

Reexamination Certificate

active

07485319

ABSTRACT:
The present invention is a solid dosage form of a doxycycline metal complex. The present invention also includes a process for making a doxycycline metal complex in a solid dosage form. The process comprises the steps of (i) providing an aqueous solution of doxycycline or a physiologically acceptable salt thereof; (ii) admixing a metal salt with the aqueous solution; (iii) admixing a base to increase the pH of the aqueous solution, thereby forming a suspension of doxycycline metal; and (iv) drying the suspension, thereby forming a dry granulation of doxycycline metal complex.

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