Double-coated granules of disodium pamidronate

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form

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Details

424457, 424458, 424459, 424461, 424462, 424468, 424494, 424497, 424470, 424489, 514108, A61K 952, A61K 954

Patent

active

050967177

ABSTRACT:
The invention relates to an advantageous oral administration from the disodium pamidronate in capsules. These capsules are filled with double-coated granules. The inner coating is hydrophilic and elastic, and the outer coating is gastric juice-resistant and intestinal juice-soluble. The granules are distinguished by good gastric compatibility.

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patent: 4786505 (1988-11-01), Lovgren et al.
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patent: 4983401 (1991-01-01), Eichel et al.
British Medical Journal 295, 1301-1305 (1987).
Br J. Cancer, 61, 123-125 (1990).
Gennaro A. (ed) Remington's Pharmaceutical Sciences 17 ed. Mack Publishing Company, pp. 1633-1643 (1985).

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