Surgery – Respiratory method or device – Means for mixing treating agent with respiratory gas
Patent
1996-06-07
2000-06-20
Lewis, Aaron J.
Surgery
Respiratory method or device
Means for mixing treating agent with respiratory gas
12820023, A61M 1500
Patent
active
060765216
DESCRIPTION:
BRIEF SUMMARY
FIELD OF INVENTION
The present invention relates to a dose indicating device intended to be provided on an inhalator, preferably a breath-actuated dry-powder inhalator, designed for multiple doses of a medicament containing an active substance, the inhalator having operating means comprising a maneuvering element for loading one dose of the medicament to a dosing unit and providing said dose in a position for inhalation as described in the first part of claim 1.
BACKGROUND OF THE INVENTION
Today most multi dose inhalators used for treatment of diseases in the bronchial area have no dose indicating device or have a device only indicating when the storage compartment is empty.
There is a strong desire among the users of such inhalators, patients as well as treating doctors and especially among parents having children using dry powder inhalators, that the inhalators should be provided with dose a indicating device indicating each and every dose as well as the number of doses fed from the storage of the medicament in order to be able to see how many doses are left in the inhalator. This could also be used to determine how many doses have been fed during a certain period of time in order to establish the correct form of therapy.
PRIOR ART
In the multi dose breath-actuated dry-powder inhalator of the type described schematically in EP-A-0 069715 and EP-A-0 237 507 and sold under trademark Turbuhaler.RTM., a dose indicating device has been built into the construction. This dose indicating device indicates both when 20 doses of the medicament are left in the storage chamber of the inhalator and when no medicament for inhalation is left. This indicating device is described in EP-A-0 258 238.
For this type of inhalator there has also been constructed a dose indicating device indicating every 25th dose until there are only 20 doses left and an indication of every 5th dose thereafter. Such a device can be seen in WO SE93/00389.
The known devices are all more or less inaccurate and do not provide a dose indicating system where each and every dose fed is indicated and/or registered. Furthermore all known indicating devices provided in such inhalators are not only complicated to produce in themself but also make the hole production of the inhalators more complicated. Such devices are also expensive and take a lot of space within the inhalators.
THE INVENTION
The present invention is set out to provide a dose indicating device which solves the above mentioned problems.
According to the invention there is provided a dose indicating device which is provided as a separate unit to be placed on the maneuvering element of the inhalator. The dose indicating device comprises a first element to be provided on and around the maneuvering element, a second element provided on and around the outer surface of said first element, said second element being rotatable relative to said first element, interrupting means provided on said first and second elements limiting the length of the relative movement between said elements, and registration/indication means for registration of the movement of the maneuvering element and thereby the feeding of a dose to the inhalation channel when the inhalator is activated for inhalation said registration/indication means being provided as parts of said first and second elements as described in the characterising part of claim 1.
As every turning of the maneuvering element, and thereby the dosing unit, will move a dose in the dosing unit from the position where it is loaded into the dosing unit to a position in the inhalation channel ready for inhalation the construction of the dose indicating means as described in claim 1 will register and indicate each and every dose activated for inhalation. The device is also easy to manufacture, to mount on the maneuvering element of the inhaler and to use for the patient.
The dose indicating device is thereby constructed as a unit to be placed on the maneuvering element of the operating means of an inhalator of the above mentioned type. If preferred it c
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PCT International Search Report.
PCT International-Type Search Report (4 pages).
Lindahl Jan-Eric
Wetterlin Kjell
Astra Aktiebolag
Lewis Aaron J.
Mitchell Teena
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