Surgery – Respiratory method or device – Means for mixing treating agent with respiratory gas
Patent
1994-11-14
1996-08-27
Burr, Edgar S.
Surgery
Respiratory method or device
Means for mixing treating agent with respiratory gas
12820312, 12820321, 12820523, 12820014, 604 58, A61M 1500
Patent
active
055491014
DESCRIPTION:
BRIEF SUMMARY
TECHNICAL FIELD OF THE INVENTION
The present invention relates to a dosage inhalator for dispensing to a patient a pharmacologically active compound or substance suspended in a fluid comprising a nozzle, a conduit connected to said nozzle, a storage means adjacent said conduit containing multiple doses of said active compound to be dispensed, a carrying means having portions for carrying predetermined and reproducible unit doses of said active compound, said carrying means being mounted for movement between said conduit and said storage means to position one of said portions in said conduit whereby said unit dose of said active compound located at said portion can be dispensed into the conduit said carrying menas being actuated by means of a maneuvering means.
BACKGROUND OF THE INVENTION
Dosage inhalators of the general type described above are disclosed for instance in U.S. Pat. No. 4,524,769, which is directed towards a dosing means in a dosage inhalator, and U.S. Pat. No. 4,668,218, which is directed towards a indicating means indicating the number of doses used or still remaining in a dosage dispensing means illustrated in an inhalator. In some cases it may however be advantageous that the patient is given a clear and unambiguous indication that the supply of the pharmacologically active compound is exhausted. It further is desirable with an indicating means having a design which is simple and cheap to manufacture and which in a simple way can be set automatically to the actual number of doses filled into the dosage inhalator.
SUMMARY OF THE INVENTION
These and other objects are achieved in that said inhalator comprises means for disrupting the movement of said maneuvering means directly or indirectly upon exhaustion of said active compound in said storage means. In this description the expression "disrupt" is used in the sense "to cause to break down", for instance locking the maneuvering means or allowing the maneuvering means to rotate freely in one or both rotational directions. In this way the patient is given a clear indication that the supply of compound is exhausted.
A further aspect of said inhalator is the providing of means for indicating either the number of doses remaining in said storage means or the number of doses used, said indicating means comprising a screw and nut mechanism being rotated by said intermittent movement of said carrying means, the relative movement between the screw and the nut in said mechanism being caused by said rotation being used for actuating said indicating means. The screw and nut mechanism preferably is provided with features for a quick adjustment in order to allow the indicating means to be preset easily to different numbers of doses.
In a preferred embodiment the relative movement between the screw and the nut in the screw and nut mechanism is utilized to disrupt the movement of the maneuvering means.
BRIEF DESCRIPTION OF THE DRAWINGS
FIG. 1 shows a longitudinal section through a first embodiment of the inhalator,
FIG. 2 shows a partly sectioned longitudinal view of the inhalator shown in FIG. 1,
FIG. 3 shows a cross-section through the lower part of the inhalator in FIG. 1,
FIG. 4 shows a longitudinal section through a second embodiment of the inhalator.
DETAILED DESCRIPTION OF PREFERRED EMBODIMENTS
The invention will be illustrated below as adapted to a breath-actuated inhalator intended for administering a solid pharmacologically active compound in micronized form of the general kind described in U.S. Pat. No. 4,524,769. The expressions "upper", "lower" etc are only used below with reference to the orientation of the inhalator for instance FIG. 1 and are not to be construed as limiting. As shown in Figs 1-3, the inhalator in a first embodiment comprises a housing 1 on which a nozzle 2 is mounted. The housing contains a conduit 3 for conducting ambient air through the housing to the nozzle 2 when the patient inhales through the inhalator. The housing further contains a storage chamber 4 for the micronized compound. The compound is transferre
REFERENCES:
patent: 4524769 (1985-06-01), Wetterlin
patent: 4668218 (1987-05-01), Virtanen
patent: 4817822 (1989-04-01), Rand et al.
patent: 5033463 (1991-07-01), Cocozza
Trofast Eva A.
Virtanen Risto K. V.
Wetterlin Kjell I. L.
Astra Aktiebolag
Burr Edgar S.
Srivastava V.
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