Surgery – Diagnostic testing – Detecting nuclear – electromagnetic – or ultrasonic radiation
Patent
1998-06-02
1999-12-21
Getzow, Scott M.
Surgery
Diagnostic testing
Detecting nuclear, electromagnetic, or ultrasonic radiation
A61B 502
Patent
active
060061286
ABSTRACT:
A method for generating a velocity-indicating, tomographic image of a sample in an optical coherence tomography system includes the steps of (a) acquiring cross-correlation data from the interferometer; (b) generating a grayscale image from the cross-correlation data indicative of a depth-dependent positions of scatterers in the sample; (c) processing the cross-correlation data to produce a velocity value and location of a moving scatterer in the sample; (d) assigning a color to the velocity value; and (f) merging the color into the grayscale image, at a point in the grayscale image indicative of the moving scatterer's location, to produce a velocity-indicating, tomographic image. Preferably a first color is assigned for a positive velocity value and a second color is assigned for a negative velocity value.
REFERENCES:
patent: 4063549 (1977-12-01), Beretsky et al.
patent: 5158090 (1992-10-01), Waldman et al.
patent: 5200819 (1993-04-01), Nudelman et al.
patent: 5353802 (1994-10-01), Ollmar
patent: 5459570 (1995-10-01), Swanson et al.
patent: 5491524 (1996-02-01), Hellmuth et al.
patent: 5493109 (1996-02-01), Wei et al.
patent: 5501226 (1996-03-01), Petersen et al.
patent: 5549114 (1996-08-01), Petersen et al.
patent: 5565986 (1996-10-01), Knuttel
patent: 5644642 (1997-07-01), Kirschbaum
Optical Coherence-Domain Reflectometry: A New Optical Evaluation Technique, R.C. Youngquist et al., Optics Letters, vol. 12, No. 3, pp. 158-160 (Mar. 1997).
Optical Coherence Tomography, D. Huang et al., Science, vol. 254, pp. 1178-1181 (Nov. 22, 1991).
Systems and Transforms with Applications in Optics, A. Papoulis, pp. 254-293, McGraw-Hill Book Company (1968).
Maximum-Likelihood Deconvolution, A Journey into Model-Based Signal Processing, J.M. Mendel, pp. 1-77, Springer-Verlag New York Inc. (1990).
Micron-Resolution Biomedical Imaging With Optical Coherence Tomography, J. Izatt et al., Optics & Photonics News (Oct. 1993).
Characterization of fluid flow velocity by optical Doppler tomography, X. Wang et al., Optics Letters, vol. 20, No. 11 (Jun. 1, 1995).
Optical Doppler tomography imaging of fluid flow velocity in highly scattered media, Z. Chen et al., Optics Letters, vol. 22, No. 1, pp. 64-66 (Jan. 1, 1997).
Distributed laser Doppler velocimeter, V. Gusmeroli et al., Optics Letters, vol. 16, No. 17 (Sep. 1, 1991).
Noninvasive imaging of in vivo blood flow velocity using optical Doppler tomography, Z. Chen et al., Optics Letters, vol. 22, No. 14 (Jul. 15, 1997).
Cleo '97: Summaries of papers presented at the Conference on Lasers and Electro-Optics, 1997 OSA Technical Digest Series, vol. 11, Conference Edition, pp. 211-212, Baltimore, MD (May, 18-23, 1997).
Real-time Two Dimensional Blood Flow Imaging Using an Autocorrelation Technique, C. Kasai et al., IEEE Transactions on Sonics and Ultrasonics, vol. SU-32, No. 3 (May 1985).
Doppler Ultrasound: Physics, Instrumentation, and Clinical Applications, Chapter 6: Basic Doppler Electronics and Signal Processing, D.H. Evans et al., pp. 84-107, John Wiley & Sons, New York (1989).
Vascular Diagnosis, 4.sup.th Ed., Chapter 12: Principles and pitfalls of real-time color flow imaging, F.W. Kremkau, pp. 90-105, Mosby Year-Book, Inc. Missouri (1993).
Vascular Diagnosis, 4.sup.th Ed., Chapter 11: Pulsed Doppler ultrasound for blood velocity measurements, K.W. Beach et al., pp. 83-89, Mosby Year-Book, Inc., Missouri (1993).
Velocity-estimation accuracy and frame-rate limitations in color Doppler optical coherence tomography, M.D. Kulkarni et al., Optics Letters, vol. 23, No. 13 (Jul. 1, 1998).
Investigating laser-blood vessel interaction with color Doppler optical coherence tomography, J.K. Barton et al., Progress in Biomedical Optics: Proceedings of Coherence Domain Optical Methods in Biomedical Science and Clinical Applications II, San Jose CA, SPIE, vol. 3251 (Jan. 27-28, 1998).
Diagnostic blood flow monitoring during therapeutic interventions using color Doppler optical coherence tomography, S. Yazdanfar et al., Progress in Biomedical Optics: Proceedings of Coherence Domain Optical Methods in Biomedical Science and Clinical Applications II, San Jose, CA, SPIE, vol. 3251 (Jan. 27-28, 1998).
High Resolution imaging of in vivo cardiac dynamics using color Doppler optical coherence tomography, S. Yazdanfar et al., Optics Express, vol. 1, No. 13 (Dec. 22, 1997).
In vivo bidirectional color Doppler flow imaging of picoliter blood volumes using optical coherence tomography, J.A. Izatt et al., Optics Letters, vol. 22, No. 18 (Sep. 15, 1997).
In vivo Doppler flow imaging of picoliter blood volumes using optical coherence tomography, J.A. Izatt et al., Cleo '97: Summaries of papers presented at the Conference on Lasers and Electro-Optics, 1997 OSA Technical Digest Series, vol.11, Conference Edition, Baltimore, MD (May 18-23, 1997).
Optical Coherence Tomography for Biodiagnostics, J.A. Izatt et al., Optics & Photonicvs News (May 1997).
Doppler Flow Imaging Using Optical Coherence Tomography, J.A. Izatt et al., Cleo '96 Postdeadline Papers, Conference on Lasers and Electro-Optics, Anaheim, CA (Jun. 02-07, 1996).
Model for laser Doppler measurements of blood flow in tissue, R. Bonner et al., Applied Optics, vol. 20, No. 12 (Jun. 15, 1981).
Izatt Joseph A.
Kulkarni Manish D.
Rollins Andrew
Sivak Michael V.
Yazdanfar Siavash
LandOfFree
Doppler flow imaging using optical coherence tomography does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Doppler flow imaging using optical coherence tomography, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Doppler flow imaging using optical coherence tomography will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-515123