Dopaminergic stimulating piperidin-3-yl-indoles

Details Dopaminergic stimulating piperidin-3-yl-indoles Dopaminergic stimulating piperidin-3-yl-indoles

1982-07-06

1984-05-08

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

546201, A01K 31445, C07D40104

Patent

active

044474385

ABSTRACT:
Novel piperidin-3-yl-indoles of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, alkyl of 1 to 8 carbon atoms and aralkyl of 7 to 12 carbon atoms, X is selected from the group consisting of hydrogen, halogen and alkyl of 1 to 8 carbon atoms or with c is .dbd.0, Y is alkyl of 1 to 8 carbon atoms, c and d form a carbon-carbon bond or c with X is .dbd.0 and d is hydrogen, Z is selected from the group consisting of hydrogen, alkyl of 1 to 8 carbon atoms, hydroxyalkyl of 2 to 8 carbon atoms, cycloalkylalkyl of 4 to 12 carbon atoms, alkenyl and alkynyl of 3 to 8 carbon atoms, aryloxyalkyl of 7 to 12 carbon atoms and aralkyl of 7 to 12 carbon atoms optionally substituted with at least one member of the group consisting of halogen, alkoxy and alkyl of 1 to 4 carbon atoms, --OH, --CF.sub.3, --OCF.sub.3. --NO.sub.2 and --NH.sub.2 and their non-toxic, pharmaceutically acceptable acid addition salts possessing remarkable dopaminergic stimulating properties and antianoxic properties and their preparation.

REFERENCES:
patent: 4196209 (1980-04-01), Dumont et al.
patent: 4332808 (1982-06-01), Guillaume et al.

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