Dopaminergic neurotrophic factor for treatment of Parkinson's di

Details Dopaminergic neurotrophic factor for treatment of Parkinson's di Dopaminergic neurotrophic factor for treatment of Parkinson's di

1991-12-09

1993-06-01

Wityshyn, Michael G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 2, A61K 3702

Patent

active

052159698

ABSTRACT:
Dopaminergic Neurotrophic Factor (DNTF), derived from cells of the peripheral nervous system, is administered to patients suffering from Parkinson's Disease in an amount effective to facilitate survival of substantia nigra dopamine nerve cells.

REFERENCES:
patent: 4701407 (1987-10-01), Appel
Collier et al. Experimental Neurology, vol. 114 pp. 343-350 (1991).
Theonen et al., Rev. Physiol. Biochem. Pharmacol., 109: 145-178 (1987).
Whittemore et al., Brain Research Review, 12: 439-464 (1987).
Tomozawa et al., Brain Research, 399: 111-124 (1986).
Windebank et al., Brain Research, 385: 197-200 (1986).
Dal Toso et al., J. Neuroscience: 8: 733-745 (1988).
Araujo et al., Brain Research, 484: 130-138 (1989).

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